Sano is dealing with a hamstring injury that doesn’t allow him to run. Perkins is bothered by back spasms for the second time in a week. Perkins, who is second in the American League in saves, won’t accompany the team on the road trip to Houston starting Friday.

Sano, who has 14 home runs in his first 50 major-league games, has played through the hamstring injury. But Minnesota manager Paul Molitor decided to rest Sano on Thursday.

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