LEADING OFF: Will the Red Sox take another shot at Machado?

A look at what’s happening around Major League Baseball on Wednesday:

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BEAN-TOWN

Manny Machado will see whether Red Sox are going to throw at him again. Still simmering from Machado’s slide that injured Dustin Pedroia less than two weeks, Boston took another shot at the Baltimore star when Chris Sale’s fastball sailed behind his legs Monday night at Fenway Park.

”I’ve lost mad respect for that team and that organization,” Machado said in an expletive-filled tirade after the game. ”If they’re going to hit me, hit me. Go ahead. Get it over with. Don’t keep lingering it around and doing that.”

Red Sox reliever Matt Barnes was suspended for throwing behind Machado’s head two days after the slide. Sale was unapologetic, saying, ”Whatever, man. I’m not losing sleep tonight.”

The Orioles and Boston still have two more games left in this series.

BACK AT IT

Cubs ace Jake Arrieta seeks a bounce-back start against Philadelphia after allowing 12 earned runs in 16 innings over his last three starts. He has allowed five homers in that stretch, a troubling spike compared to the 10 he allowed in 229 innings while winning the NL Cy Young Award in 2015. Jerad Eickhoff (0-2, 3.56) is up for the Phillies at Wrigley Field.

FINGERS CROSSED

Indians and Rangers fans may learn more about the status of star pitchers Corey Kluber and Cole Hamels. Kluber was pulled from Cleveland’s game against Detroit on Tuesday because of back discomfort. Kluber allowed five runs in three innings, his shortest outing in nearly a year. Hamels was scratched from his scheduled start for Texas against Houston because of tightness in his right oblique. He’s set to meet with team physician Keith Meister in Arlington, Texas.

ROCKY ROAD

Nationals right-hander A.J. Cole is back up from the minors, though he can’t pitch yet. Washington promoted him from Triple-A this week, but he first must serve the final three games of a five-game suspension he drew last September for throwing a pitch near the head of Pittsburgh’s Jung Ho Kang. Cole missed a large portion of the 2016 season with shoulder trouble.

POPULAR AND PRODUCTIVE

Toronto righty Marcus Stroman often has his own cheering section when he pitches at Yankee Stadium – he grew nearby on Long Island. He is 5-2 with a 2.17 ERA in eight career starts against the Yankees going into this outing vs. CC Sabathia and New York.